Egg studies found mixed gut-related results and higher short-term blood choline
In healthy adults, pooled studies found higher blood choline, while other blood-marker results were nonsignificant. Associations with particular gut bacteria varied.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
For healthy adults, this review found conflicting evidence about whole eggs and gut-related outcomes. Blood choline increased over ≤4 weeks. Pooled TMAO and C-reactive protein results were not statistically significant, but their timing was not separately clear. Associations between usual egg intake and particular gut bacteria varied in direction. These findings do not establish improved gastrointestinal health.
The review included intervention and observational studies. The abstract gives no effect sizes or comparison diets for the pooled blood results, limiting interpretation of what changed and by how much.
Blood markers and symptoms
The pooled analyses measured blood choline, trimethylamine N-oxide, abbreviated TMAO, and C-reactive protein. These measurements do not directly show symptom relief. The abstract does not report a pooled result for gastrointestinal symptoms.
Bacterial associations were inconsistent
Studies of usual egg intake found associations in opposite directions with bacteria that produce butyrate. These correlations do not establish that eggs caused the bacterial differences, or that a difference in those bacteria improved gastrointestinal health.
The original publication
The Impact of Egg Consumption on Gastrointestinal Health: A Systematic Literature Review and Meta-Analysis.
Sultan N, Tuck CJ, Cheng E et al.
Nutrients · 2025
- PubMed ID
- 40647165
- Record checked
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