Higher admission blood-sugar ratios were associated with worse critical-illness outcomes
A review linked a blood-test ratio with mortality and major cardiovascular events in critically ill patients, but supplied no effect sizes or prediction-accuracy estimates.
Based on the published abstract. The full paper may contain additional methods, results and limitations.
The 30-second takeaway
In critically ill patients, a higher blood-sugar-based ratio at admission was associated with more deaths and major cardiovascular events. This review combined observational studies, so the result does not show that the ratio causes these outcomes. The abstract supplies no effect estimates or prediction-accuracy measures, leaving the strength and practical usefulness of the association unclear.
The abstract omits comparison thresholds, effect estimates, confidence intervals and measures of predictive accuracy. This abstract-based explanation cannot establish how well the ratio identifies individual patients who will have poor outcomes.
What the ratio measures
The stress hyperglycemia ratio compares blood glucose with glycated hemoglobin at admission. It is calculated from blood measurements. The review examined its relationship with later outcomes, rather than testing a treatment that changed the ratio.
Separate mortality outcomes
The reported associations included mortality within 30 days and 1 year, cardiovascular deaths and deaths from any cause. These are separate endpoints. The abstract does not provide estimates that would allow their association strengths to be compared.
The original publication
Predictive performance of stress hyperglycemia ratio for poor prognosis in critically ill patients: a systematic review and dose-response meta-analysis.
Chen L, Zeng X, Zou W et al.
Eur J Med Res · 2025
- PubMed ID
- 40646634
- Record checked
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