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Ankle blood pressure averaged higher than arm pressure

In adults without peripheral artery disease, ankle and arm readings differed. A prediction model estimated arm pressure better than fixed formulas.

By 100HP editorialAbstract-based explanation checked

Based on the published abstract. The full paper may contain additional methods, results and limitations.

The 30-second takeaway

Among the included adults, ankle systolic blood pressure was higher on average than arm pressure. A model using multiple variables estimated arm pressure more accurately than fixed arithmetic formulas. This supports better prediction of a measurement, but the abstract does not establish that using the model improves treatment decisions or health outcomes.

Keep in mind

People with peripheral artery disease were excluded. This abstract-based brief cannot assess detailed model performance across patient groups, and the abstract does not report outcome follow-up duration.

THE NUMBERS, WITH CONTEXT

What researchers found

12.0 mm Hg higher

Mean ankle versus arm systolic blood pressure

Measurements taken lying down; 95% confidence interval for the mean difference: 8.8 to 15.2 mm Hg. Measurement timing was not reported.

BMJ Open, 2025 · Original source ↓

Why the average needs care

The average difference describes the pooled measurements. Researchers also developed and validated a model to estimate arm pressure from ankle pressure; it performed better than existing fixed arithmetic formulas.

Health outcomes were examined separately

Pressure from the lower-reading ankle was associated with cardiovascular events. Neither overall nor cardiovascular mortality showed a statistically significant association with ankle pressure. These observational findings cannot establish causation, and nonsignificance does not demonstrate no association.

CHECK THE ORIGINAL

The original publication

Arm Based on LEg blood pressures (ABLE-BP): can systolic ankle blood pressure measurements predict systolic arm blood pressure? An individual participant data meta-analysis from the INTERPRESS-IPD Collaboration.

McDonagh STJ, Warren FC, Sheppard JP et al.
BMJ Open · 2025

PubMed ID
40500230
Record checked

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